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MSI B650 Gaming Plus WiFi Motherboard AMD B650 vs ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX

Updated August 2026 — MSI B650 Gaming Plus WiFi Motherboard AMD B650 wins on design, ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX wins on performance and connectivity.

The MSI B650 Gaming Plus offers great value for gamers, while the Pro WS W680-ACE is better suited for professional use.

Why MSI B650 Gaming Plus WiFi Motherboard AMD B650 is better

Price

MSI is about 50% cheaper than ASUS.

Gaming Focus

Designed specifically for gaming with Ryzen support.

Aesthetics

Sleek design appealing to gamers.

Why ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX is better

Performance

Better suited for demanding professional tasks.

Connectivity

Includes Thunderbolt 4 and dual 2.5Gb Ethernet.

Expansion

More M.2 slots for versatile storage options.

Overall score

MSI B650 Gaming Plus WiFi Motherboard AMD B650
75
ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX
85

Specifications

SpecMSI B650 Gaming Plus WiFi Motherboard AMD B650ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX
SocketAM5LGA 1700
PCIe Slots2x PCIe 4.02x PCIe 5.0
Memory TypeDDR5DDR5 ECC
M.2 Slots23
Wi-FiWi-Fi 6ENo

Dimension comparison

MSI B650 Gaming Plus WiFi Motherboard AMD B650ASUS Pro WS W680-ACE Intel W680 LGA 1700 ATX

Pricing Comparison

The MSI B650 Gaming Plus WiFi motherboard is priced at $171.54, while the Pro WS W680-ACE Intel W680 motherboard costs significantly more at $339.25. This makes the MSI option about 50% cheaper than its ASUS counterpart. For budget-conscious users or gamers looking to build a powerful PC without breaking the bank, the MSI B650 Gaming Plus offers significant savings. However, it's essential to consider whether the lower price comes with any compromises in features or performance.

Performance Capabilities

In terms of performance, the MSI B650 Gaming Plus is designed for gaming with support for Ryzen 9000 series processors. It features a 12+2 Duet Rail VRM, which is excellent for stable power delivery during intense gaming sessions. The Pro WS W680-ACE, on the other hand, is tailored for professional use, supporting 13th and 12th Gen Intel Core processors. It includes dual PCIe 5.0 slots and an enhanced power solution, making it better suited for demanding tasks like AI training and 3D rendering. While both motherboards aim for high performance, their target audiences differ significantly.

Memory and Expansion Slots

The MSI B650 Gaming Plus supports DDR5 memory with four DIMM slots, allowing for overclocking capabilities up to 6400+ MHz. It also has two PCIe 4.0 x16 slots for graphics cards, which is ample for gaming setups. Conversely, the Pro WS W680-ACE supports ECC memory and also includes dual PCIe 5.0 slots, making it more future-proof for high-end computing tasks. The ASUS model's additional M.2 slots (three total) allow for versatile storage options, while the MSI's dual M.2 slots focus on gaming performance. Users seeking maximum expansion potential may gravitate towards the Pro WS W680-ACE.

Connectivity Features

Connectivity is another area where the two motherboards diverge. The MSI B650 Gaming Plus includes Wi-Fi 6E and Bluetooth 5.3, along with a 2.5Gbps LAN connection, providing gamers with fast and reliable network performance. In contrast, the Pro WS W680-ACE features dual Intel 2.5Gb Ethernet ports and Thunderbolt 4 header support, which is crucial for professional environments that require high-speed data transfer. While both motherboards offer impressive connectivity options, the ASUS model caters more to professionals needing advanced networking capabilities.

Cooling Solutions

Cooling solutions are essential for maintaining performance, especially under heavy loads. The MSI B650 Gaming Plus is equipped with a dedicated pump-fan cooling header and several passive cooling features, including an extended heatsink and MOSFET thermal pads. This is particularly useful for gamers who push their hardware to the limit. Meanwhile, the Pro WS W680-ACE boasts a large VRM heatsink and M.2 heatsinks, along with hybrid fan headers. These features are designed for prolonged stability during intensive workloads, making it a better choice for users involved in tasks such as deep learning or media production.

Design and Aesthetics

Aesthetic appeal can influence a user's choice between the two motherboards. The MSI B650 Gaming Plus sports a sleek, gamer-oriented design, making it attractive for those who prioritize aesthetics in their builds. The Pro WS W680-ACE, however, adopts a more professional appearance suited for workstations, which may be preferable for users who want their hardware to fit into a professional environment. Ultimately, the choice between the two may come down to personal preference regarding design.

User Experience and Support

User experience can vary significantly between the two brands. MSI is known for its gamer-friendly software and support, which can enhance the overall user experience for gamers. In contrast, ASUS's Pro WS series is recognized for its centralized management software, beneficial for IT administrators and professionals managing multiple systems. Depending on the intended use, users might find the support and software features more aligned with their needs in one brand over the other.

Which should you buy?

In conclusion, the choice between the MSI B650 Gaming Plus WiFi and the Pro WS W680-ACE largely depends on the intended use. The MSI motherboard is a fantastic option for gamers seeking high performance at a more affordable price, while the Pro WS W680-ACE is tailored for professionals needing advanced features and connectivity for demanding applications. If budget is a primary concern, the MSI B650 is about 50% cheaper, but for those who require the utmost reliability and performance in a professional setting, investing in the ASUS motherboard may be worthwhile.