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Brooks Women’s Glycerin 21 Neutral Running Shoe - vs Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8

Updated August 2026 — Brooks Women’s Glycerin 21 Neutral Running Shoe - wins on price, Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 wins on weight and comfort.

The Brooks Glycerin 21 excels in comfort and cushioning, while the Saucony Endorphin Pro 4 is designed for speed and performance. Choose based on your running priorities.

Why Brooks Women’s Glycerin 21 Neutral Running Shoe - is better

Price

Glycerin 21 is cheaper by $15.71

Cushioning

Glycerin 21 offers superior softness

Versatility

Glycerin 21 is suitable for various activities

Why Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 is better

Performance

Endorphin Pro 4 is designed for race-day speed

Technology

Endorphin Pro 4 features advanced carbon plate

Popularity

Endorphin Pro 4 has a higher sales rank

Overall score

Brooks Women’s Glycerin 21 Neutral Running Shoe -
78
Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8
85

Specifications

SpecBrooks Women’s Glycerin 21 Neutral Running Shoe -Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8
CushioningDNA Loft v3PWRRUN PB
Support TypeNeutralPerformance
WeightHeavierLighter
Sales Rank2988113551
Price$114.95$130.66

Dimension comparison

Brooks Women’s Glycerin 21 Neutral Running Shoe -Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8

Overview of Running Shoes

When comparing the Brooks Women’s Glycerin 21 Neutral Running Shoe and the Saucony Women's Endorphin Pro 4 Sneaker, it's clear that each shoe caters to different types of runners. The Glycerin 21 is priced at $114.95, while the Endorphin Pro 4 is priced at $130.66, making the Brooks shoe about 17% cheaper. This difference in price may influence the decision for budget-conscious runners or those seeking value without sacrificing quality.

Comfort and Cushioning

The Brooks Women’s Glycerin 21 is designed for those who prioritize comfort. It offers super-soft cushioning, thanks to nitrogen-infused DNA Loft v3 technology. This shoe is perfect for runners seeking plush comfort during their runs. In contrast, the Saucony Women's Endorphin Pro 4 focuses on a snappier, performance-oriented feel, featuring a carbon plate that enhances responsiveness. While the Glycerin 21 excels in softness, the Endorphin Pro 4 caters to runners looking for speed and agility.

Support and Stability

The Glycerin 21 provides neutral support with a broad platform that stabilizes the foot and ensures smooth transitions during runs. This is particularly beneficial for road runners and those engaging in cross-training. On the other hand, the Endorphin Pro 4 is engineered for race-day performance, featuring cutting-edge technology such as PWRRUN PB cushioning and SPEEDROLL technology. While both shoes prioritize different aspects of support, the Glycerin 21’s focus on stability may appeal to more casual runners, whereas the Endorphin Pro 4 targets competitive athletes.

Design and Aesthetics

In terms of design, the Glycerin 21 showcases a sleek black, grey, and white color scheme that is both stylish and versatile, making it suitable for various athletic and casual settings. The Endorphin Pro 4 stands out with its eye-catching Mirage/Citron colorway, appealing to those who want a more vibrant look. Personal preference will largely dictate which aesthetic resonates more with potential buyers, but both shoes are visually appealing in their own right.

Weight and Performance

The Brooks Glycerin 21 is designed with an emphasis on comfort rather than weight, making it a go-to option for long-distance runs. The Endorphin Pro 4, however, is engineered to be lightweight and responsive, making it ideal for runners looking for speed. While specific weight data is not provided, the performance characteristics of each shoe suggest that the Endorphin Pro 4 would be preferred by those participating in races or speed workouts, while the Glycerin 21 suits longer, more leisurely runs.

Price Comparison

The price point is a significant factor for many consumers. The Brooks Women’s Glycerin 21 is available for $114.95, while the Saucony Women's Endorphin Pro 4 retails at $130.66. This price difference of about $15.71 may make the Glycerin 21 more appealing for budget-conscious runners. Additionally, the Glycerin 21’s consistent sales rank of 29,881 suggests it is well-regarded in its category, while the Endorphin Pro 4’s higher sales rank of 13,551 indicates strong popularity among competitive runners.

Usage Scenarios

The Glycerin 21 is ideal for runners who prioritize cushioning and comfort, making it suitable for long runs, gym sessions, and casual wear. Its neutral support is well-suited for a variety of activities beyond running. Conversely, the Endorphin Pro 4 is tailored for race-day performance, making it the perfect choice for competitive runners aiming to improve their speed and efficiency. Each shoe fulfills distinct needs, and runners should consider their specific usage scenarios when choosing between them.

Which should you buy?

Deciding between the Brooks Women’s Glycerin 21 and the Saucony Women's Endorphin Pro 4 ultimately depends on your running style and preferences. If comfort and plush cushioning are your priorities, the Glycerin 21 at $114.95 is an excellent choice. However, if you’re looking for a lightweight shoe that enhances your speed and performance on race day, the Endorphin Pro 4 at $130.66 may be worth the investment. Both shoes have their strengths, so consider what aspects of running are most important to you before making a decision.