Brooks Women’s Ghost 17 Neutral Running vs Brooks Women’s Glycerin 22 Neutral
Updated April 2026 — Brooks Women’s Ghost 17 Neutral Running wins on value and versatility, Brooks Women’s Glycerin 22 Neutral wins on cushioning and fit.
$114.95Brooks Women’s Glycerin 22 Neutral Running Shoe - White/Limpet Shell/Amparo Blue - 8.5 Medium
Brooks
The {{PRODUCT_B_NAME}} edges out the {{PRODUCT_A_NAME}} with its latest DNA Tuned cushioning technology and maximum cushioning design, offering a more plush experience for runners prioritizing softness. However, the {{PRODUCT_A_NAME}} remains a strong contender for those seeking a carbon-neutral option at a slightly lower price point while maintaining essential certifications.
Why Brooks Women’s Ghost 17 Neutral Running is better
{{PRODUCT_A_NAME}} offers a lower retail price
$110.00 vs $114.95
{{PRODUCT_A_NAME}} is a certified carbon neutral product
Environmental status confirmed
{{PRODUCT_A_NAME}} features specific forefoot cushioning increase
Extra 3mm in forefoot
Why Brooks Women’s Glycerin 22 Neutral is better
{{PRODUCT_B_NAME}} utilizes the latest DNA Tuned technology
Dual-size cells integration
{{PRODUCT_B_NAME}} provides maximum amount of cushioning
Premium plush design
{{PRODUCT_B_NAME}} features newly engineered upper
Double jacquard knit
Overall score
Specifications
| Spec | Brooks Women’s Ghost 17 Neutral Running | Brooks Women’s Glycerin 22 Neutral |
|---|---|---|
| Price | $110.00 | $114.95 |
| Cushioning Technology | DNA LOFT v3 | DNA Tuned |
| Support Type | Neutral | Neutral |
| Diabetic Certification | PDAC A5500 | PDAC A5500 |
| APMA Seal | Yes | Yes |
| Predecessor Model | Ghost 16 | Glycerin 21 |
| Carbon Status | Carbon Neutral | Not Mentioned |
| Upper Construction | Not Specified | Double Jacquard Knit |
| Heel Cushioning Update | Extra 1mm | Larger Cells |
| Forefoot Cushioning Update | Extra 3mm | Smaller Cells |
Dimension comparison
Introduction and Overview
The running shoe market offers numerous options for neutral runners seeking comfort and reliability. Two prominent models from Brooks stand out in this category: the {{PRODUCT_A_NAME}} and the {{PRODUCT_B_NAME}}. Both shoes are designed to provide neutral support and are suitable for a variety of activities beyond running, including walking and cross-training. While they share the same brand heritage and core certification standards, they utilize different midsole technologies and target slightly different preferences within the neutral running segment. This comparison evaluates their features to help buyers determine which model aligns best with their needs.
Cushioning and Midsole Technology
Cushioning is a primary differentiator between these two models. The {{PRODUCT_A_NAME}} features DNA LOFT v3 cushioning, which is nitrogen-infused to deliver lightweight softness. Notably, this version includes an extra 1mm of cushioning in the heel and 3mm in the forefoot compared to its predecessor. In contrast, the {{PRODUCT_B_NAME}} introduces DNA Tuned, the latest midsole technology from the brand. This system seamlessly blends and integrates dual-size cells, aiming to balance luxurious cushioning with energetic toe-offs. The {{PRODUCT_B_NAME}} is described as offering the maximum amount of cushioning in the lineup.
Support and Stability Features
Both shoes are designed for neutral support, meaning they do not include additional stability mechanisms for overpronation. The {{PRODUCT_A_NAME}} is built to be an everyday companion providing smooth, reliable comfort for runners and walkers alike. Similarly, the {{PRODUCT_B_NAME}} provides neutral support while focusing on plush landings. For runners requiring added support, the brand suggests looking for the GTS version of the {{PRODUCT_B_NAME}}, indicating that the standard model reviewed here is strictly neutral. Both models aim to maintain speed and momentum through their respective designs.
Fit and Upper Construction
The upper construction plays a significant role in the overall comfort and fit of a running shoe. The {{PRODUCT_B_NAME}} features a newly engineered double jacquard knit upper. This design is intended to deliver a flexible and accommodating fit while combining durability with exceptional breathability. The specific upper material for the {{PRODUCT_A_NAME}} is not detailed in the provided specifications, though it is designed for comfort. The accommodating fit of the {{PRODUCT_B_NAME}} may appeal to those seeking a modern knit experience, while the {{PRODUCT_A_NAME}} focuses on a reliable standard fit.
Versatility and Activity Range
Versatility is a strong suit for both options, as they are not limited strictly to road running. The {{PRODUCT_A_NAME}} is ideal for road running, walking, cross training, travel, and the gym. It is marketed as an everyday companion. The {{PRODUCT_B_NAME}} is also ideal for road running, cross training, the gym, or wherever you might want to take them. Both shoes are designed to handle multiple environments, making them suitable choices for individuals who prefer a single pair of shoes for various physical activities throughout their week.
Certifications and Health Standards
Health and accessibility certifications are identical across both models, which is a significant factor for many buyers. Both the {{PRODUCT_A_NAME}} and the {{PRODUCT_B_NAME}} are certified PDAC A5500 Diabetic shoes. Additionally, both have been granted the APMA Seal of Acceptance. These certifications indicate that both shoes meet specific standards for therapeutic footwear and have been evaluated by podiatric medical professionals. This parity ensures that users requiring diabetic-certified footwear can choose based on other performance factors without compromising on medical standards.
Pricing and Value Proposition
Price often dictates the final decision for many consumers. The {{PRODUCT_A_NAME}} is listed at $110.00, while the {{PRODUCT_B_NAME}} is priced at $114.95. The {{PRODUCT_A_NAME}} holds a slight advantage in affordability. Furthermore, the {{PRODUCT_A_NAME}} is a certified carbon neutral product, which may add value for environmentally conscious consumers. The {{PRODUCT_B_NAME}} commands a higher price point, likely justified by its status as the maximum cushioning option and the inclusion of the newer DNA Tuned technology. Value depends on whether the buyer prioritizes cost and sustainability or premium cushioning tech.
Final Recommendation
Choosing between these two Brooks models depends on specific runner priorities. The {{PRODUCT_B_NAME}} is the recommended choice for runners seeking the softest possible ride with the latest midsole technology and a modern knit upper. It edges out the competition in pure cushioning performance. However, the {{PRODUCT_A_NAME}} is an excellent alternative for those who want a reliable neutral shoe with verified eco-friendly credentials at a lower price point. Both shoes offer essential health certifications, ensuring safety and comfort for a wide range of users.
