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Brooks Women’s Glycerin 22 Neutral vs Brooks Women’s Glycerin 23 Neutral

Updated April 2026 — Brooks Women’s Glycerin 22 Neutral wins on price and value, Brooks Women’s Glycerin 23 Neutral wins on technology and cushioning technology.

Brooks Women’s Glycerin 22 Neutral Running Shoe - White/Limpet Shell/Amparo Blue - 8.5 Medium$114.95

Brooks Women’s Glycerin 22 Neutral Running Shoe - White/Limpet Shell/Amparo Blue - 8.5 Medium

Brooks

Winner
Brooks Women’s Glycerin 23 Neutral Running Shoe - White/Phantom/Cyber Pink - 8.5 Medium$159.99

Brooks Women’s Glycerin 23 Neutral Running Shoe - White/Phantom/Cyber Pink - 8.5 Medium

Brooks

The {{PRODUCT_B_NAME}} edges out the {{PRODUCT_A_NAME}} with upgraded nitrogen-infused cushioning and a triple jacquard upper, offering superior comfort for long distances. However, the {{PRODUCT_A_NAME}} remains a strong value proposition for runners seeking certified neutral support at a lower price point.

Why Brooks Women’s Glycerin 22 Neutral is better

Lower Price Point

Costs $114.95 compared to $159.99

Better Value Proposition

Offers core neutral support features at a lower cost

Established Lineage

Follows the Glycerin 21 predecessor with proven design

Why Brooks Women’s Glycerin 23 Neutral is better

Enhanced Forefoot Cushioning

Includes 2mm more cushioning in the forefoot

Advanced Upper Material

Features triple jacquard warp-knit vs double jacquard knit

Nitrogen-Infused Midsole

Upgraded Zonal DNA Tuned with nitrogen infusion

Overall score

Brooks Women’s Glycerin 22 Neutral
86
Brooks Women’s Glycerin 23 Neutral
89

Specifications

SpecBrooks Women’s Glycerin 22 NeutralBrooks Women’s Glycerin 23 Neutral
Price$114.95$159.99
Midsole TechnologyDNA TunedZonal DNA Tuned (Nitrogen-infused)
Upper ConstructionDouble jacquard knitTriple jacquard warp-knit
Forefoot CushioningStandard DNA Tuned cells2mm more cushioning
Support TypeNeutralNeutral
Diabetic CertificationPDAC A5500PDAC A5500
APMA SealYesYes
Predecessor ModelGlycerin 21Glycerin 22

Dimension comparison

Brooks Women’s Glycerin 22 NeutralBrooks Women’s Glycerin 23 Neutral

Design and Build Quality

The {{PRODUCT_A_NAME}} and {{PRODUCT_B_NAME}} both represent the pinnacle of Brooks' neutral running shoe lineup, designed specifically for women seeking premium comfort. Both models feature a structured design intended to accommodate various foot shapes while maintaining durability. The build quality in both iterations focuses on balancing flexibility with structural integrity, ensuring the shoe holds up over repeated miles. While the external silhouettes share a familial resemblance, the internal engineering distinguishes the two generations significantly.

Cushioning Technology

At the heart of the comparison lies the midsole technology. The {{PRODUCT_A_NAME}} utilizes DNA Tuned cushioning, which integrates dual-size cells to blend luxurious cushioning with energetic toe-offs. This system is designed to provide soft landings and responsive transitions. In contrast, the {{PRODUCT_B_NAME}} introduces an upgraded Zonal DNA Tuned midsole. This newer iteration is nitrogen-infused and specifically engineered to include 2mm more cushioning in the forefoot. This adjustment aims to create softer landings and more responsive toe-offs, delivering a luxurious feel with every step while supporting consistent performance across longer distances.

Upper Construction and Fit

The upper construction plays a critical role in the overall fit and breathability of the shoe. The {{PRODUCT_A_NAME}} employs a newly engineered double jacquard knit upper. This material is selected to deliver a flexible and accommodating fit, combining durability with exceptional breathability. Moving to the newer model, the {{PRODUCT_B_NAME}} features a newly enhanced triple jacquard warp-knit upper. This upgrade is designed to deliver a plush, comfortable fit with just the right amount of stretch and structure. The modern upper wraps the foot securely while reducing hot spots, offering a more refined interface between the foot and the shoe.

Support and Stability

Both shoes are categorized under neutral support, making them ideal for runners who do not require additional stability features for overpronation. The {{PRODUCT_A_NAME}} provides neutral support while offering the maximum amount of cushioning, suitable for road running, cross training, or gym use. Similarly, the {{PRODUCT_B_NAME}} is designed for neutral runners seeking premium comfort and smooth performance. For those who require added support, Brooks directs users to the GTS versions of these models, but within this comparison, both stand as flagship neutral options designed to handle daily training without corrective intervention.

Comfort and Feel

Comfort is the primary objective for the Glycerin line, and both models strive to achieve a distraction-free experience. The {{PRODUCT_A_NAME}} focuses on smooth transitions, ensuring that the blend of dual-size cells works seamlessly to balance cushioning and energy return. The {{PRODUCT_B_NAME}} takes this further by emphasizing fluid transitions so runners can focus on enjoying every mile, regardless of pace or distance. The adaptive foam in the newer model supports consistent performance, aiming to reduce fatigue during long runs or recovery days where plush cushioning is paramount.

Certification and Safety

Both models share important certifications that highlight their suitability for specific medical and comfort needs. The {{PRODUCT_A_NAME}} is a certified PDAC A5500 Diabetic shoe and has been granted the APMA Seal of Acceptance. This ensures that the shoe meets specific standards for therapeutic footwear. The {{PRODUCT_B_NAME}} maintains these same certifications, being a certified PDAC A5500 Diabetic shoe with the APMA Seal of Acceptance. This consistency ensures that users relying on these certifications for health reasons can upgrade models without losing compliance or accepted safety standards.

Price and Value

Price is a significant differentiator between these two generations. The {{PRODUCT_A_NAME}} is listed at $114.95, positioning it as a more accessible option within the premium neutral category. The {{PRODUCT_B_NAME}} carries a higher price tag of $159.99, reflecting the updates in technology and materials. For budget-conscious runners, the older model offers substantial value, providing core Glycerin features at a lower cost. However, for those prioritizing the latest cushioning advancements, the price increase for the newer model may be justified by the tangible upgrades in the midsole and upper construction.

Which One Should You Buy?

Choosing between the {{PRODUCT_A_NAME}} and the {{PRODUCT_B_NAME}} depends on your priorities regarding technology versus budget. If you seek the latest in cushioning technology with nitrogen-infused foam and enhanced upper comfort for long distances, the {{PRODUCT_B_NAME}} is the superior choice. However, if you want a certified neutral shoe with proven DNA Tuned cushioning at a more affordable price point, the {{PRODUCT_A_NAME}} remains an excellent option. Both shoes offer APMA acceptance and diabetic certification, ensuring high standards of care regardless of which generation you select.