Brooks Women’s Glycerin 22 Neutral vs Brooks Women’s Glycerin 23 Neutral
Updated April 2026 — Brooks Women’s Glycerin 22 Neutral wins on price and value, Brooks Women’s Glycerin 23 Neutral wins on technology and cushioning technology.
$114.95Brooks Women’s Glycerin 22 Neutral Running Shoe - White/Limpet Shell/Amparo Blue - 8.5 Medium
Brooks
$159.99Brooks Women’s Glycerin 23 Neutral Running Shoe - White/Phantom/Cyber Pink - 8.5 Medium
Brooks
The {{PRODUCT_B_NAME}} edges out the {{PRODUCT_A_NAME}} with upgraded nitrogen-infused cushioning and a triple jacquard upper, offering superior comfort for long distances. However, the {{PRODUCT_A_NAME}} remains a strong value proposition for runners seeking certified neutral support at a lower price point.
Why Brooks Women’s Glycerin 22 Neutral is better
Lower Price Point
Costs $114.95 compared to $159.99
Better Value Proposition
Offers core neutral support features at a lower cost
Established Lineage
Follows the Glycerin 21 predecessor with proven design
Why Brooks Women’s Glycerin 23 Neutral is better
Enhanced Forefoot Cushioning
Includes 2mm more cushioning in the forefoot
Advanced Upper Material
Features triple jacquard warp-knit vs double jacquard knit
Nitrogen-Infused Midsole
Upgraded Zonal DNA Tuned with nitrogen infusion
Overall score
Specifications
| Spec | Brooks Women’s Glycerin 22 Neutral | Brooks Women’s Glycerin 23 Neutral |
|---|---|---|
| Price | $114.95 | $159.99 |
| Midsole Technology | DNA Tuned | Zonal DNA Tuned (Nitrogen-infused) |
| Upper Construction | Double jacquard knit | Triple jacquard warp-knit |
| Forefoot Cushioning | Standard DNA Tuned cells | 2mm more cushioning |
| Support Type | Neutral | Neutral |
| Diabetic Certification | PDAC A5500 | PDAC A5500 |
| APMA Seal | Yes | Yes |
| Predecessor Model | Glycerin 21 | Glycerin 22 |
Dimension comparison
Design and Build Quality
The {{PRODUCT_A_NAME}} and {{PRODUCT_B_NAME}} both represent the pinnacle of Brooks' neutral running shoe lineup, designed specifically for women seeking premium comfort. Both models feature a structured design intended to accommodate various foot shapes while maintaining durability. The build quality in both iterations focuses on balancing flexibility with structural integrity, ensuring the shoe holds up over repeated miles. While the external silhouettes share a familial resemblance, the internal engineering distinguishes the two generations significantly.
Cushioning Technology
At the heart of the comparison lies the midsole technology. The {{PRODUCT_A_NAME}} utilizes DNA Tuned cushioning, which integrates dual-size cells to blend luxurious cushioning with energetic toe-offs. This system is designed to provide soft landings and responsive transitions. In contrast, the {{PRODUCT_B_NAME}} introduces an upgraded Zonal DNA Tuned midsole. This newer iteration is nitrogen-infused and specifically engineered to include 2mm more cushioning in the forefoot. This adjustment aims to create softer landings and more responsive toe-offs, delivering a luxurious feel with every step while supporting consistent performance across longer distances.
Upper Construction and Fit
The upper construction plays a critical role in the overall fit and breathability of the shoe. The {{PRODUCT_A_NAME}} employs a newly engineered double jacquard knit upper. This material is selected to deliver a flexible and accommodating fit, combining durability with exceptional breathability. Moving to the newer model, the {{PRODUCT_B_NAME}} features a newly enhanced triple jacquard warp-knit upper. This upgrade is designed to deliver a plush, comfortable fit with just the right amount of stretch and structure. The modern upper wraps the foot securely while reducing hot spots, offering a more refined interface between the foot and the shoe.
Support and Stability
Both shoes are categorized under neutral support, making them ideal for runners who do not require additional stability features for overpronation. The {{PRODUCT_A_NAME}} provides neutral support while offering the maximum amount of cushioning, suitable for road running, cross training, or gym use. Similarly, the {{PRODUCT_B_NAME}} is designed for neutral runners seeking premium comfort and smooth performance. For those who require added support, Brooks directs users to the GTS versions of these models, but within this comparison, both stand as flagship neutral options designed to handle daily training without corrective intervention.
Comfort and Feel
Comfort is the primary objective for the Glycerin line, and both models strive to achieve a distraction-free experience. The {{PRODUCT_A_NAME}} focuses on smooth transitions, ensuring that the blend of dual-size cells works seamlessly to balance cushioning and energy return. The {{PRODUCT_B_NAME}} takes this further by emphasizing fluid transitions so runners can focus on enjoying every mile, regardless of pace or distance. The adaptive foam in the newer model supports consistent performance, aiming to reduce fatigue during long runs or recovery days where plush cushioning is paramount.
Certification and Safety
Both models share important certifications that highlight their suitability for specific medical and comfort needs. The {{PRODUCT_A_NAME}} is a certified PDAC A5500 Diabetic shoe and has been granted the APMA Seal of Acceptance. This ensures that the shoe meets specific standards for therapeutic footwear. The {{PRODUCT_B_NAME}} maintains these same certifications, being a certified PDAC A5500 Diabetic shoe with the APMA Seal of Acceptance. This consistency ensures that users relying on these certifications for health reasons can upgrade models without losing compliance or accepted safety standards.
Price and Value
Price is a significant differentiator between these two generations. The {{PRODUCT_A_NAME}} is listed at $114.95, positioning it as a more accessible option within the premium neutral category. The {{PRODUCT_B_NAME}} carries a higher price tag of $159.99, reflecting the updates in technology and materials. For budget-conscious runners, the older model offers substantial value, providing core Glycerin features at a lower cost. However, for those prioritizing the latest cushioning advancements, the price increase for the newer model may be justified by the tangible upgrades in the midsole and upper construction.
Which One Should You Buy?
Choosing between the {{PRODUCT_A_NAME}} and the {{PRODUCT_B_NAME}} depends on your priorities regarding technology versus budget. If you seek the latest in cushioning technology with nitrogen-infused foam and enhanced upper comfort for long distances, the {{PRODUCT_B_NAME}} is the superior choice. However, if you want a certified neutral shoe with proven DNA Tuned cushioning at a more affordable price point, the {{PRODUCT_A_NAME}} remains an excellent option. Both shoes offer APMA acceptance and diabetic certification, ensuring high standards of care regardless of which generation you select.