Brooks Women’s Ghost 17 Neutral Running Shoe - vs Nike Women's Run Defy Road Running Shoes,
Updated July 2026 — Brooks Women’s Ghost 17 Neutral Running Shoe - wins on price and cushioning, Nike Women's Run Defy Road Running Shoes, wins on sales rank.
The Brooks Women’s Ghost 17 offers superior cushioning and versatility, making it the better choice for serious runners, while the Nike Women’s Run Defy is a budget-friendly option for casual use.
Why Brooks Women’s Ghost 17 Neutral Running Shoe - is better
Cushioning
Brooks features advanced nitrogen-infused DNA Loft v3 cushioning.
Sales Rank
Brooks has a higher sales rank at 61 compared to Nike's 11,383.
Versatility
Brooks is suitable for multiple activities including cross-training.
Why Nike Women's Run Defy Road Running Shoes, is better
Price
Nike is significantly cheaper at $65 compared to Brooks at $110.
Weight
Nike emphasizes flexibility and lightweight design.
Simplicity
Nike's design is straightforward and appeals to casual users.
Overall score
Specifications
| Spec | Brooks Women’s Ghost 17 Neutral Running Shoe - | Nike Women's Run Defy Road Running Shoes, |
|---|---|---|
| Brand | Brooks | Nike |
| Current Price | $110.00 | $65.00 |
| Cushion Type | DNA Loft v3 | Foam |
| Upper Material | Air Mesh | Mesh |
| Outsole Type | Rubber | Waffle |
Dimension comparison
Overview of the Brooks Women’s Ghost 17 and Nike Women’s Run Defy
The Brooks Women’s Ghost 17 is priced at $110.00, while the Nike Women’s Run Defy is significantly cheaper at $65.00, making it about 41% less expensive. Both shoes cater to runners and walkers, but they differ in features, comfort, and intended use. The Ghost 17 has a higher sales rank, sitting at 61, indicating it is a more popular choice among consumers compared to the Run Defy, which ranks at 11,383.
Comfort and Cushioning
When it comes to comfort, the Brooks Women’s Ghost 17 excels with its premium nitrogen-infused DNA Loft v3 cushioning, designed for a soft and responsive ride. This shoe features a precise flex groove midsole that promotes smooth transitions, making it ideal for long runs. In contrast, the Nike Women’s Run Defy utilizes a foam midsole that delivers a soft ride but lacks the advanced cushioning technology found in the Ghost 17. The Ghost 17's focus on comfort and cushioning makes it an excellent choice for those looking for a shoe that can handle daily wear and longer distances.
Breathability
Breathability is a crucial factor in running shoes, and both models have unique attributes. The Brooks Ghost 17 features a double jacquard air mesh upper that ensures optimal airflow, keeping feet cool and dry during intense activities. On the other hand, the Nike Run Defy also has a mesh upper, promoting breathability but not specified to the same extent as Brooks. While both shoes offer decent ventilation, the Ghost 17 may provide a slight edge for runners prioritizing breathability in warmer conditions.
Weight and Performance
The Brooks Women’s Ghost 17 is built for performance with a lightweight feel, owing to its innovative rubber outsole crafted with recycled silica. This design enhances durability and responsiveness, which is crucial for runners looking to maintain speed over various terrains. The Nike Women’s Run Defy, while also lightweight, emphasizes flexibility with its Waffle outsole, designed for traction and durability. However, it may not offer the same level of performance as the Ghost 17, particularly for serious runners looking for that extra responsiveness.
Versatility
In terms of versatility, the Brooks Ghost 17 is suitable for a range of activities, including road running, walking, cross-training, travel, and gym workouts. Its design caters well to those who require a multi-purpose shoe. The Nike Run Defy, while also versatile, may be more suited for casual running and light training due to its simpler construction and focus on comfort rather than performance. For individuals seeking a shoe that can adapt to various activities, the Ghost 17 stands out as the more versatile option.
Design and Aesthetics
The aesthetics of both shoes appeal to different tastes. The Brooks Women’s Ghost 17 comes in a stylish White/Black/Rose Gold color scheme, which can appeal to those looking for a trendy yet functional running shoe. In comparison, the Nike Women’s Run Defy features a clean White/Pure Platinum-Black design, offering a classic look that is also appealing. While both designs are visually appealing, the choice ultimately comes down to individual preference regarding style.
Price Comparison
The price difference between the Brooks Women’s Ghost 17 and the Nike Women’s Run Defy is significant. With the Ghost 17 priced at $110.00 and the Run Defy at $65.00, the Nike option is about 41% cheaper. This price point may attract budget-conscious consumers who still want a reliable running shoe. However, it’s important to consider that the Ghost 17’s higher price reflects its premium features and performance capabilities, which might justify the investment for serious runners.
Which should you buy?
Ultimately, the choice between the Brooks Women’s Ghost 17 and the Nike Women’s Run Defy depends on your specific needs and budget. If you are a serious runner looking for advanced cushioning, breathability, and versatility, the Brooks Ghost 17 is the superior option despite its higher price. However, if you are seeking a budget-friendly, comfortable shoe for casual running or walking, the Nike Run Defy offers great value without compromising on essential features. Consider your running habits and preferences to make the best choice for your footwear needs.

