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Brooks Women’s Glycerin 21 Neutral Running Shoe - vs New Balance Women's Fresh Foam X More V6 Running

Updated August 2026 — Brooks Women’s Glycerin 21 Neutral Running Shoe - wins on price and cushioning, New Balance Women's Fresh Foam X More V6 Running wins on style and weight.

The Brooks Women’s Glycerin 21 offers superior cushioning and comfort at a lower price, making it a great choice for long runs. The New Balance Women's Fresh Foam X More V6 is lighter and stylish, ideal for those prioritizing speed and modern aesthetics.

Why Brooks Women’s Glycerin 21 Neutral Running Shoe - is better

Price

Glycerin 21 is $114.95, cheaper than Fresh Foam X at $159.95.

Cushioning

Glycerin 21 features nitrogen-infused DNA Loft v3 cushioning for superior softness.

Comfort

Glycerin 21 provides a plush internal fit and smooth transitions.

Why New Balance Women's Fresh Foam X More V6 Running is better

Weight

Fresh Foam X weighs only 8.5 oz, making it lighter.

Reflectivity

Fresh Foam X has reflective details for visibility during runs.

Secure Fit

Fresh Foam X features a gusseted tongue for a snug fit.

Overall score

Brooks Women’s Glycerin 21 Neutral Running Shoe -
88
New Balance Women's Fresh Foam X More V6 Running
82

Specifications

SpecBrooks Women’s Glycerin 21 Neutral Running Shoe -New Balance Women's Fresh Foam X More V6 Running
Current Price$114.95$159.95
Sales Rank2988125188
WeightNot listed8.5 oz
Cushion TypeDNA Loft v3Fresh Foam X
ReflectiveNoYes

Dimension comparison

Brooks Women’s Glycerin 21 Neutral Running Shoe -New Balance Women's Fresh Foam X More V6 Running

Overview of the Brooks Women’s Glycerin 21

The Brooks Women’s Glycerin 21 is a neutral running shoe designed for runners who value super-soft cushioning and comfort. Priced at $114.95, it is about 28% cheaper than its competitor, the New Balance Women's Fresh Foam X More V6, which retails for $159.95. This price difference may appeal to budget-conscious shoppers looking for quality running shoes without breaking the bank.

The Glycerin 21 features a plush internal fit and soft transitions that enhance comfort during runs. This shoe has been recognized with the APMA Seal of Acceptance, which adds credibility to its design for neutral support. With a sales rank of 29,881, it reflects a solid presence in the market, catering to runners who prioritize cushioning and support.

Overview of the New Balance Women's Fresh Foam X More V6

The New Balance Women's Fresh Foam X More V6 is a lightweight running shoe priced at $159.95. It offers a midsole designed for maximum cushioning, making it an excellent choice for those seeking comfort during their runs. The shoe weighs only 8.5 ounces, making it a great option for runners who prefer a lighter feel as they move.

With a sales rank of 25,188, the Fresh Foam X More V6 has a slightly better market position compared to the Glycerin 21. The shoe's reflective details make it ideal for early morning or evening runs, adding a layer of safety for nighttime workouts. Additionally, the gusseted tongue design ensures a secure fit, enhancing the overall running experience.

Cushioning and Comfort

When it comes to cushioning, the Brooks Women’s Glycerin 21 excels with its nitrogen-infused DNA Loft v3 cushioning, providing a plush experience designed to absorb impact effectively. This shoe is particularly well-suited for runners who prioritize comfort on long runs, thanks to its soft internal fit and smooth transitions.

On the other hand, the New Balance Women’s Fresh Foam X More V6 features a Fresh Foam X midsole, touted as the most cushioned Fresh Foam experience available. While both shoes are designed for comfort, the Brooks model offers a more substantial level of softness, making it better for those who prefer a cushy feel underfoot. The Glycerin 21's cushioning is optimized for responsiveness, which can enhance performance during runs.

Fit and Support

The Brooks Women’s Glycerin 21 is designed to offer a plush improved fit with its internal stretch bootie, which accommodates the foot's natural movements. This design promotes stability and comfort, making it suitable for various activities beyond just running.

Conversely, the New Balance Women's Fresh Foam X More V6 also provides a secure fit, thanks to its gusseted tongue design. This feature helps maintain a snug fit without compromising breathability. However, the Glycerin 21 may appeal more to runners who desire a softer, more enveloping feel, while the Fresh Foam X More V6 is better suited for those looking for a lightweight and secure lockdown fit.

Weight Considerations

The Brooks Women’s Glycerin 21 does not explicitly list its weight, but it is designed with maximum cushioning in mind, which typically results in a slightly heavier shoe. This shoe prioritizes comfort over weight, ideal for runners who are less concerned about the weight of their footwear.

In contrast, the New Balance Women's Fresh Foam X More V6 weighs just 241 grams (8.5 oz), making it a lightweight option for runners who want to maintain a fast pace. This difference in weight can significantly impact performance, especially for competitive runners. The lighter Fresh Foam X More V6 may be more suitable for speed training and shorter runs, while the Glycerin 21 is better for long-distance comfort.

Versatility in Use

The Brooks Women’s Glycerin 21 is marketed as versatile enough for road running, cross-training, and gym workouts. Its neutral support and plush cushioning make it adaptable to various activities, appealing to those who engage in multiple forms of exercise.

The New Balance Women’s Fresh Foam X More V6 also offers versatility, performing well as a running shoe and a general lifestyle sneaker. Its lightweight design and breathability make it suitable for all-day wear, which can be advantageous for those who transition from workouts to casual outings. However, the Glycerin 21 may provide a slight edge in comfort for longer runs due to its superior cushioning.

Aesthetic Appeal

The Brooks Women’s Glycerin 21 comes in a black, grey, and white color scheme, appealing to those who prefer classic and understated aesthetics. This timeless look may attract runners who want footwear that can blend in with various outfits.

In contrast, the New Balance Women’s Fresh Foam X More V6 features a stylish sea salt, lab green, and frosted glass color combination. Its modern design might appeal to younger runners or those looking for a fresh, trendy look. The choice between these styles ultimately depends on personal taste and how much importance one places on aesthetics in running shoes.

Which should you buy?

Choosing between the Brooks Women’s Glycerin 21 and the New Balance Women’s Fresh Foam X More V6 ultimately depends on your specific running needs. If you prioritize maximum cushioning, comfort, and a plush fit, the Glycerin 21 is an excellent choice, especially given its lower price of $114.95. However, if you prefer a lightweight shoe with a secure fit and modern style, the Fresh Foam X More V6 at $159.95 may be more appealing. Both options cater to different types of runners, so assessing your personal preferences and running habits will guide you to the right choice.