Brooks Women’s Adrenaline GTS 25 Supportive vs Brooks Women’s Glycerin GTS 22 Supportive Running
Updated July 2026 — Brooks Women’s Adrenaline GTS 25 Supportive leads on price and support.
The Brooks Adrenaline GTS 25 offers better support and a structured fit, while the Glycerin GTS 22 provides a more plush cushioning experience.
Why Brooks Women’s Adrenaline GTS 25 Supportive is better
Support
Adrenaline GTS 25 has a superior GuideRails support system.
Cushioning
Adrenaline GTS 25 features nitrogen-infused DNA LOFT v3 cushioning.
Fit Options
Adrenaline GTS 25 is available in multiple widths.
Why Brooks Women’s Glycerin GTS 22 Supportive Running is better
Price
Glycerin GTS 22 is $18.04 cheaper.
Cushioning
Glycerin GTS 22 offers a more plush cushioning experience.
Versatility
Glycerin GTS 22 is suitable for various activities.
Overall score
Specifications
| Spec | Brooks Women’s Adrenaline GTS 25 Supportive | Brooks Women’s Glycerin GTS 22 Supportive Running |
|---|---|---|
| ASIN | B0F4JY3X33 | B0D38FWJ8M |
| Color | Spellbound/Blazing Bell/Pink | White/Limpet Shell/Amparo Blue |
| Sales Rank | 459 | 2097 |
| Cushion Type | DNA LOFT v3 | DNA Tuned |
| Upper Material | Engineered Mesh | Double Jacquard Knit |
Dimension comparison
Overview of the Brooks Adrenaline GTS 25 and Brooks Glycerin GTS 22
The Brooks Women’s Adrenaline GTS 25 is priced at $132.99, while the Brooks Women’s Glycerin GTS 22 is about 14% cheaper at $114.95. Both shoes are designed for runners and walkers, offering excellent support and cushioning, but they cater to slightly different preferences and needs.
The Adrenaline GTS 25 features a GuideRails support system and nitrogen-infused DNA LOFT v3 cushioning, making it ideal for those seeking a reliable and smooth ride. In contrast, the Glycerin GTS 22 employs DNA Tuned technology for luxurious cushioning and energetic toe-offs. This article will delve into the key differences and similarities between these two popular running shoes.
Design and Aesthetics
When it comes to design, both the Adrenaline GTS 25 and Glycerin GTS 22 boast stylish aesthetics that appeal to a wide range of users. The Adrenaline GTS 25 is available in a striking Spellbound/Blazing Bell/Pink color scheme, while the Glycerin GTS 22 comes in a more understated White/Limpet Shell/Amparo Blue combination.
The Adrenaline GTS 25’s engineered mesh upper offers a secure and breathable fit, contributing to its sleek profile. Meanwhile, the Glycerin GTS 22 features a double jacquard knit upper that combines durability with exceptional breathability, ensuring a flexible and accommodating fit. Ultimately, your choice may come down to personal preference in color and design.
Comfort and Cushioning
In terms of comfort, the Brooks Adrenaline GTS 25 shines with its nitrogen-infused DNA LOFT v3 cushioning, providing lightweight softness and a smooth ride. This shoe features 3 mm of added cushioning in the forefoot, enhancing comfort during runs and walks.
On the other hand, the Glycerin GTS 22 incorporates DNA Tuned technology, which consists of dual-size cells in the midsole. This design ensures plush landings and responsive toe-offs, making it perfect for those who prioritize cushioning. Both shoes are designed to promote comfort, but the Glycerin GTS 22 offers a more plush experience, while the Adrenaline GTS 25 focuses on a balance between support and cushioning.
Support Features
Support is a critical factor in running shoes, and both the Adrenaline GTS 25 and Glycerin GTS 22 excel in this area. The Adrenaline GTS 25 employs a GuideRails holistic support system that helps maintain your body’s natural motion path, minimizing excess movement and ensuring stability. This feature is particularly beneficial for runners prone to overpronation.
Conversely, the Glycerin GTS 22 also includes the GuideRails support system, but it is designed to provide a slightly different experience by blending luxurious cushioning with stabilization. This shoe is particularly suited for those who engage in various activities, such as road running and cross-training. Both shoes offer outstanding support, but the Adrenaline GTS 25 may be better for those seeking a more structured fit.
Fit and Sizing
When it comes to fit, the Brooks Adrenaline GTS 25 is available in multiple widths, accommodating a wide range of foot shapes. Its flat-knit collar and breathable upper ensure a secure fit, allowing for natural movement without discomfort.
The Glycerin GTS 22 also offers an accommodating fit with its engineered double jacquard knit upper, which provides flexibility and breathability. Both shoes cater to different foot types, but the Adrenaline GTS 25’s additional width options make it a more versatile choice for those with specific sizing needs.
Performance on Different Terrains
The Brooks Adrenaline GTS 25 and Glycerin GTS 22 are primarily designed for road running, but their performance can also extend to various terrains. The Adrenaline GTS 25 features a specially designed outsole and midsole that promote smooth transitions, ensuring comfort and support with every step.
The Glycerin GTS 22, with its broad platform, stabilizes the foot and smooths heel-to-toe transitions, making it suitable for diverse environments. While both shoes excel on roads, the Glycerin GTS 22’s cushioning may be more forgiving on uneven surfaces. For runners who frequently switch terrains, the Glycerin GTS 22 may offer a slight edge in adaptability.
Durability and Build Quality
Durability is an essential consideration when investing in running shoes. The Brooks Adrenaline GTS 25 is built with high-quality materials, including an engineered mesh upper and rubber outsole, ensuring longevity even with regular use. Its PDAC A5500 certification further emphasizes its suitability for diabetic wearers, making it a reliable choice.
Similarly, the Glycerin GTS 22 boasts a robust construction with a double jacquard knit upper that enhances durability and breathability. Both shoes are designed to withstand the rigors of running, but the Adrenaline GTS 25’s focus on support may make it more appealing to those who prioritize long-lasting wear.
Which should you buy?
Choosing between the Brooks Women’s Adrenaline GTS 25 and the Brooks Women’s Glycerin GTS 22 ultimately depends on your specific needs and preferences. If you prioritize a structured fit with excellent support and prefer a shoe that offers a balance of cushioning and stability, the Adrenaline GTS 25 is an excellent choice at $132.99.
However, if you’re looking for a more plush experience and a versatile shoe suitable for various activities, the Glycerin GTS 22 at $114.95 may be the better option for you. With its luxurious cushioning and supportive features, you can’t go wrong with either choice, but understanding your running style and terrain preferences will guide you to the right decision.

