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Brooks Women’s Glycerin 22 Neutral Running Shoe - vs Brooks Women’s Trace 4 Neutral Running Shoe -

Updated August 2026 — Brooks Women’s Glycerin 22 Neutral Running Shoe - wins on support and cushioning, Brooks Women’s Trace 4 Neutral Running Shoe - wins on price and weight.

The Brooks Women’s Glycerin 22 offers superior cushioning and stability, making it ideal for long-distance runners, while the Trace 4 is a more budget-friendly option with good comfort.

Why Brooks Women’s Glycerin 22 Neutral Running Shoe - is better

Cushioning

Glycerin 22 features advanced DNA Tuned technology for luxurious cushioning.

Stability

Glycerin 22 has a broad platform for enhanced stability.

Support

Glycerin 22 is certified as a PDAC A5500 Diabetic shoe.

Why Brooks Women’s Trace 4 Neutral Running Shoe - is better

Price

Trace 4 is $23.20 cheaper than Glycerin 22.

Weight

Trace 4 is designed to be lighter for quicker transitions.

Breathability

Trace 4 features an engineered air mesh upper for better breathability.

Overall score

Brooks Women’s Glycerin 22 Neutral Running Shoe -
88
Brooks Women’s Trace 4 Neutral Running Shoe -
75

Specifications

SpecBrooks Women’s Glycerin 22 Neutral Running Shoe -Brooks Women’s Trace 4 Neutral Running Shoe -
Price$114.95$91.75
Sales Rank84412197
Cushion TypeDNA TunedDNA LOFT v2
Upper MaterialDouble Jacquard KnitEngineered Air Mesh
Support TypeNeutralNeutral

Dimension comparison

Brooks Women’s Glycerin 22 Neutral Running Shoe -Brooks Women’s Trace 4 Neutral Running Shoe -

Overview of the Brooks Women’s Glycerin 22 and Trace 4

When comparing the Brooks Women’s Glycerin 22 and the Brooks Women’s Trace 4, the Glycerin 22 is a premium option priced at $114.95, while the Trace 4 offers a more budget-friendly choice at $91.75. The Glycerin 22 is designed for runners seeking maximum cushioning and smooth transitions, while the Trace 4 focuses on comfort and adaptability for various running styles. This price difference of about 17% may influence buyers depending on their budget and performance needs.

Comfort and Cushioning

The Glycerin 22 features advanced DNA Tuned technology that combines dual-size cells to provide luxurious cushioning and energetic toe-offs, making it a great choice for those prioritizing comfort. In contrast, the Trace 4 utilizes DNA LOFT v2 cushioning, which is also designed for comfort but emphasizes lightweight adaptability. While both shoes excel in cushioning, the Glycerin 22's focus on plush landings could be more appealing for long-distance runners. The Glycerin 22's emphasis on smooth transitions and stability adds to its overall comfort, especially for those who value soft landings during their runs.

Support and Stability

For support, the Glycerin 22 is classified under neutral support and is certified as a PDAC A5500 Diabetic shoe, highlighting its suitability for various foot types. It features a broad platform that enhances stability during runs. The Trace 4, while also providing neutral support, focuses on creating a smooth transition with its segmented crash pad and sculpted grooves in the outsole. This difference makes the Glycerin 22 better for runners who may need additional stability, while the Trace 4 is ideal for those who prefer a more flexible ride.

Fit and Breathability

In terms of fit, the Glycerin 22 boasts a newly engineered double jacquard knit upper that offers a flexible and accommodating fit, ensuring durability and breathability. The Trace 4, on the other hand, incorporates an engineered air mesh upper that enhances breathability and keeps runners dry. While both shoes are designed for comfort, the Glycerin 22’s fit may appeal more to those who prioritize a snug feel, while the Trace 4’s breathable upper is excellent for warmer weather conditions.

Weight and Performance

The Glycerin 22 is designed for optimal performance with its plush cushioning, which may make it slightly heavier than the Trace 4. The Trace 4, with its lightweight DNA LOFT v2 cushioning, aims to provide an adaptable ride for runners seeking a lighter option. This difference in weight could be crucial for runners looking for speed and agility, as the Trace 4 might facilitate quicker transitions. However, those who favor cushioning and stability may find the Glycerin 22 more beneficial for longer runs.

Durability and Traction

When examining durability, both shoes are constructed with high-quality materials, but the Glycerin 22's focus on a broad platform may give it an edge in stability, especially on varied terrains. The Trace 4 features a RoadTack rubber outsole designed to be durable and lightweight, making it suitable for different running surfaces. The Glycerin 22's cushioning technology also contributes to its durability by maintaining comfort over extended periods, while the Trace 4’s traction is designed for reliable performance during everyday runs.

Price Comparison

At $114.95, the Glycerin 22 is positioned as a premium running shoe, while the Trace 4 is priced at $91.75, making it a more economical option. This $23.20 difference means the Trace 4 is about 17% cheaper than the Glycerin 22. For budget-conscious runners, this price point could be a significant factor, especially for those who may not require the advanced features of the Glycerin 22. However, for those willing to invest in higher performance and enhanced cushioning, the Glycerin 22 may justify its higher price.

Which should you buy?

Deciding between the Brooks Women’s Glycerin 22 and the Trace 4 ultimately comes down to your running style and preferences. If you are a long-distance runner seeking maximum cushioning and stability, the Glycerin 22 is worth the investment for its advanced technology and smooth transitions. However, if you're looking for a more affordable option that still offers comfort and adaptability, the Trace 4 is an excellent choice. The best fit will depend on your budget, running habits, and the specific features you value in a running shoe.