Brooks Women’s Glycerin 22 Neutral Running Shoe - vs Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8
Updated August 2026 — Brooks Women’s Glycerin 22 Neutral Running Shoe - wins on versatility and comfort, Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 wins on performance.
The Brooks Glycerin 22 offers superior comfort and versatility at a lower price, while the Saucony Endorphin Pro 4 is designed for speed and performance.
Why Brooks Women’s Glycerin 22 Neutral Running Shoe - is better
Price
Brooks is $114.95 compared to Saucony's $130.66.
Comfort
Glycerin 22 features luxurious cushioning.
Versatility
Glycerin 22 is suitable for various activities.
Why Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 is better
Speed
Endorphin Pro 4 is designed for race-day performance.
Lightweight
Endorphin Pro 4 is lighter for faster runs.
Performance Tech
Endorphin Pro 4 includes advanced racing technologies.
Overall score
Specifications
| Spec | Brooks Women’s Glycerin 22 Neutral Running Shoe - | Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 |
|---|---|---|
| Brand | Brooks | Saucony |
| Current Price | $114.95 | $130.66 |
| Sales Rank | 844 | 13551 |
| Cushioning | DNA Tuned | PWRRUN |
| Weight | Light | Very Light |
Dimension comparison
Overview of the Brooks Women’s Glycerin 22 and Saucony Women’s Endorphin Pro 4
The Brooks Women’s Glycerin 22 is priced at $114.95, while the Saucony Women’s Endorphin Pro 4 costs $130.66, making the Brooks shoe about 17% cheaper. Both shoes are designed for running, but they cater to different needs and preferences, which will be explored in the following sections.
Comfort and Cushioning
The Brooks Women’s Glycerin 22 is known for its luxurious cushioning, thanks to its DNA Tuned technology, which combines larger cells in the heel for soft landings and smaller cells in the forefoot for responsive toe-offs. This feature ensures a plush experience during runs, making it ideal for road running and cross-training. In contrast, the Saucony Women’s Endorphin Pro 4 emphasizes speed with a snappy on-your-toes performance, leveraging technologies like PWRRUN HG, PWRRUN PB, and a carbon plate to enhance responsiveness. While the Glycerin 22 focuses on cushioning comfort, the Endorphin Pro 4 is designed for those looking for a lightweight and fast shoe.
Support and Stability
The Brooks Glycerin 22 offers neutral support, providing maximum cushioning without added stability features. It is well-suited for runners who prefer a natural foot movement. On the other hand, the Saucony Endorphin Pro 4 focuses on racing dynamics, which may not provide the same level of support for casual runners. The Glycerin 22’s broad platform helps stabilize the foot during transitions, making it a better choice for those who prioritize comfort over speed.
Fit and Design
The Brooks Women’s Glycerin 22 features a newly engineered double jacquard knit upper for a flexible and accommodating fit. This design not only enhances durability but also allows for exceptional breathability, catering to a wider variety of foot shapes. Conversely, the Saucony Endorphin Pro 4 is designed with a more performance-oriented fit, which may feel snugger and more restrictive. Runners should consider their personal preferences for fit when choosing between these two shoes.
Versatility
The Glycerin 22 is versatile enough for various activities, including road running, gym workouts, and cross-training, making it suitable for multi-sport athletes. It’s ideal for those who might want a single shoe for different types of training. In contrast, the Saucony Endorphin Pro 4 is tailored more toward race-day performance, which may limit its versatility for everyday training. If you're looking for a shoe that can handle a variety of activities, the Glycerin 22 stands out.
Price and Value
With a current price of $114.95, the Brooks Glycerin 22 offers a compelling value, especially considering its features like the PDAC A5500 certification and APMA Seal of Acceptance. The Saucony Endorphin Pro 4, priced at $130.66, represents a premium option intended for serious runners, but lacks some of the broader certifications that the Glycerin 22 boasts. The price difference reflects the intended use of each shoe, with the Brooks offering more for a general audience at a lower price point.
Sales and Popularity
The Brooks Glycerin 22 has a bestseller rank of 844, indicating a solid level of popularity among consumers. Meanwhile, the Saucony Endorphin Pro 4 has a higher rank of 13,551, which suggests that it may not be as widely adopted as the Glycerin 22. This disparity in sales may reflect the Glycerin's broader appeal for casual runners compared to the niche market of racing shoes represented by the Endorphin Pro 4.
Performance in Focus
The Brooks Women’s Glycerin 22 is engineered for smooth transitions and plush landings, making it an excellent choice for those prioritizing comfort and support during longer runs. The Saucony Women’s Endorphin Pro 4, however, is built for speed and agility, featuring technologies that propel the runner forward with less effort. For competitive runners looking to shave seconds off their times, the Endorphin Pro 4 is a strong contender, while the Glycerin 22 is better suited for those enjoying their runs at a more leisurely pace.
Which should you buy?
Choosing between the Brooks Women’s Glycerin 22 and the Saucony Women’s Endorphin Pro 4 depends on your specific running needs. If you prioritize comfort, support, and versatility at a lower price point, the Brooks Glycerin 22 is the better option. However, if you're an experienced runner seeking a lightweight, race-oriented shoe for speed, the Saucony Endorphin Pro 4 may be worth the investment. Ultimately, your choice should align with your running habits and goals.

