Brooks Women’s Glycerin 22 Neutral Running Shoe - vs Topo Athletic Women's Magnifly 5 Comfortable
Updated August 2026 — Brooks Women’s Glycerin 22 Neutral Running Shoe - wins on cushioning and support, Topo Athletic Women's Magnifly 5 Comfortable wins on price and weight.
The Brooks Women’s Glycerin 22 excels in cushioning and comfort, while the Topo Athletic Women's Magnifly 5 offers a lightweight and budget-friendly option. Overall, the Glycerin 22 is the better choice for serious runners.
Why Brooks Women’s Glycerin 22 Neutral Running Shoe - is better
Cushioning
Advanced DNA Tuned cushioning technology.
Support
Provides excellent neutral support.
Durability
High-quality materials ensure longevity.
Why Topo Athletic Women's Magnifly 5 Comfortable is better
Price
More budget-friendly at $99.94.
Weight
Lighter design for easier movement.
Breathability
Recycled mesh upper enhances airflow.
Overall score
Specifications
| Spec | Brooks Women’s Glycerin 22 Neutral Running Shoe - | Topo Athletic Women's Magnifly 5 Comfortable |
|---|---|---|
| Price | $114.95 | $99.94 |
| Sales Rank | 844 | 30146 |
| Drop | 10mm | 0mm |
| Upper Material | Jacquard Knit | Recycled Mesh |
| Midsole Technology | DNA Tuned | ZipFoam |
Dimension comparison
Overview of the Brooks Women’s Glycerin 22
The Brooks Women’s Glycerin 22 is a premium running shoe that focuses on delivering an elite experience for runners. Priced at $114.95, it features advanced cushioning technology and a design aimed at providing smooth transitions. The shoe incorporates the latest DNA Tuned midsole technology, which combines larger cells in the heel for plush landings with smaller cells in the forefoot for a responsive toe-off. As of now, it holds a bestseller rank of 844, indicating a solid presence among running footwear.
This shoe is particularly well-suited for neutral support, making it ideal for road running, cross-training, and gym workouts. The engineered double jacquard knit upper not only enhances durability but also ensures exceptional breathability for prolonged wear. Overall, the Glycerin 22 represents a blend of luxury and performance, making it a strong contender for serious runners.
Overview of the Topo Athletic Women's Magnifly 5
The Topo Athletic Women's Magnifly 5 is a comfortable and lightweight running shoe priced at $99.94, making it about 17% cheaper than the Brooks Women’s Glycerin 22. This shoe excels in providing versatility, catering to daily mileage, recovery runs, and even casual walking. Its breathable construction features a recycled mesh upper that enhances ventilation, ensuring comfort during extended use.
The Magnifly 5 employs Topo Athletic's innovative ZipFoam midsole, which boosts responsiveness, providing a softer and lighter ride. A unique zero-drop design is featured, promoting a natural stride and biomechanically sound gait, which can be particularly beneficial for runners focused on proper form. With a bestseller rank of 30,146, it appeals to a broad audience looking for a reliable running companion.
Comfort and Fit
When it comes to comfort, both shoes offer unique features that cater to different preferences. The Brooks Women’s Glycerin 22 is designed with DNA Tuned cushioning, which provides a plush experience while maintaining responsiveness during toe-offs. This technology is particularly beneficial for those who value comfort during long runs or extended training sessions. The double jacquard knit upper also contributes to an accommodating fit, ensuring that wearers don't feel restricted.
In contrast, the Topo Athletic Women's Magnifly 5 focuses on lightweight comfort with its breathable recycled mesh upper. This design not only enhances airflow but also makes the shoe feel less cumbersome, which is ideal for runners who prefer a lighter shoe. The cushioned midsole and zero-drop design work together to deliver a comfortable experience that encourages natural movement. Ultimately, the choice between the two may depend on whether you prioritize plush cushioning or a lighter, more breathable fit.
Performance and Responsiveness
In terms of performance, the Brooks Women’s Glycerin 22 shines with its advanced cushioning technology. The larger cells in the heel provide soft landings, which is essential for absorbing impact during road runs. The smaller forefoot cells allow for energetic toe-offs, making this shoe a great option for those who enjoy speed work or interval training.
On the other hand, the Topo Athletic Women's Magnifly 5 boasts a more responsive ride thanks to its ZipFoam midsole. This feature enhances the shoe's ability to adapt to various paces, making it suitable for both leisurely runs and faster workouts. The zero-drop design aids in maintaining a balanced stride, promoting efficiency. Runners looking for a shoe that offers versatility in performance may gravitate toward the Magnifly 5, while those seeking superior cushioning might prefer the Glycerin 22.
Durability and Build Quality
Durability is another critical factor when selecting running shoes. The Brooks Women’s Glycerin 22 is constructed with high-quality materials that ensure longevity, making it a reliable choice for frequent runners. Its engineered upper is designed to withstand wear and tear while offering excellent breathability, which is essential for maintaining comfort over time.
Conversely, the Topo Athletic Women's Magnifly 5 also emphasizes durability through its recycled mesh upper. While it may not have the same level of cushioning technology as the Glycerin 22, its lightweight build does not compromise on sturdiness. Runners who prefer a shoe that feels light yet remains durable will find the Magnifly 5 appealing. Ultimately, both shoes are built for longevity, but the Glycerin 22 may edge out slightly due to its advanced technology and materials.
Style and Aesthetic
The aesthetic appeal of footwear can significantly influence a buyer's decision. The Brooks Women’s Glycerin 22 comes in a stylish colorway of White/Limpet Shell/Amparo Blue, making it a versatile choice that can easily pair with various athletic outfits. Its sleek design is not only functional but also visually appealing, catering to those who appreciate a fashionable touch in their running gear.
In comparison, the Topo Athletic Women's Magnifly 5 features a Charcoal/Black color scheme that offers a more understated, classic look. This design may attract runners who prefer a subtle style over a more vibrant one. While both shoes have their unique aesthetics, the choice will largely depend on personal style preferences.
Price Comparison
Price is a significant factor for many buyers, and here the Topo Athletic Women's Magnifly 5 offers a more budget-friendly option at $99.94 compared to the Brooks Women’s Glycerin 22, which is priced at $114.95. This difference of about $15 may make the Magnifly 5 a more attractive choice for those who are budget-conscious or just starting their running journey. However, runners should also weigh the potential benefits of the Glycerin 22's advanced technology against the cost savings of the Magnifly 5.
Which should you buy?
Choosing between the Brooks Women’s Glycerin 22 and the Topo Athletic Women's Magnifly 5 ultimately depends on your specific running needs and preferences. If you prioritize advanced cushioning technology, superior comfort, and a stylish design, the Glycerin 22 could be the better choice for you. However, if you’re looking for a lightweight, versatile shoe that’s budget-friendly, the Magnifly 5 stands out as a solid option. Both shoes have their strengths, so consider what features matter most to you before making a decision.

