Brooks Women’s Glycerin GTS 22 Supportive Running vs Nike Women's Pegasus 41 White/White/Pure
Updated August 2026 — Brooks Women’s Glycerin GTS 22 Supportive Running leads on support and fit.
The Brooks Glycerin GTS 22 offers superior support and stability, making it ideal for various activities, while the Nike Pegasus 41 is lightweight and breathable, perfect for road running.
Why Brooks Women’s Glycerin GTS 22 Supportive Running is better
Support
Brooks features GuideRails for stability.
Versatility
Brooks is suitable for multiple activities.
Cushioning
Brooks uses DNA Tuned cushioning technology.
Why Nike Women's Pegasus 41 White/White/Pure is better
Weight
Nike is lighter due to engineered mesh.
Breathability
Nike has an upgraded breathable upper.
Price
Nike is slightly cheaper at $111.67.
Overall score
Specifications
| Spec | Brooks Women’s Glycerin GTS 22 Supportive Running | Nike Women's Pegasus 41 White/White/Pure |
|---|---|---|
| Brand | Brooks | Nike |
| Model | Glycerin GTS 22 | Pegasus 41 |
| Upper | Double Jacquard | Engineered Mesh |
| Midsole | DNA Tuned | ReactX Foam |
| Support System | GuideRails | None |
Dimension comparison
Overview of the Brooks Glycerin GTS 22 and Nike Pegasus 41
The Brooks Glycerin GTS 22 is priced at $114.95, while the Nike Pegasus 41 is slightly less expensive at $111.67, making it about 3% cheaper. Both shoes are designed for women and cater to road running enthusiasts but offer distinct features that appeal to different types of runners. The Brooks model stands out for its supportive technology, while the Nike model is known for its lightweight and breathable design.
Comfort and Cushioning
When it comes to comfort, the Brooks Glycerin GTS 22 excels with its DNA Tuned cushioning technology, providing a luxurious feel with soft landings and energetic toe-offs. This shoe features a broad platform that stabilizes the foot and promotes smooth transitions from heel to toe. In contrast, the Nike Pegasus 41 utilizes a ReactX foam midsole along with dual Air Zoom units, delivering responsive cushioning and an energized ride. While both shoes prioritize comfort, the Brooks model offers more robust support features that may appeal to those seeking stability during their runs.
Fit and Breathability
The Brooks Glycerin GTS 22 features a newly engineered double jacquard knit upper designed for a flexible and accommodating fit, ensuring durability and breathability. This design element makes it suitable for various activities, including road running and cross-training. On the other hand, the Nike Pegasus 41 boasts an upgraded breathable engineered mesh upper, which not only reduces weight but also enhances airflow. While both shoes offer a comfortable fit, the Brooks Glycerin GTS 22 may be preferable for runners who prioritize a more supportive and adaptive structure over sheer breathability.
Stability Features
Stability is a crucial aspect for many runners, especially those who may overpronate. The Brooks Glycerin GTS 22 employs the innovative GuideRails holistic support system, which keeps excess motion in check while allowing for a natural motion path. This feature is particularly beneficial for runners looking for that extra layer of support. In comparison, the Nike Pegasus 41 doesn’t emphasize stability to the same extent, focusing instead on delivering a lightweight experience with its engineered mesh and ReactX foam. If stability is a top priority, the Brooks Glycerin GTS 22 has a definitive edge.
Performance and Versatility
In terms of performance, the Brooks Glycerin GTS 22 is ideal for those seeking a versatile shoe that can handle various activities, including cross-training and gym workouts. Its smooth, stable transitions make it suitable for different terrains. Meanwhile, the Nike Pegasus 41 is designed primarily for road running, offering a responsive and energized ride. Although both shoes can be used for running, the Brooks model’s versatility may appeal more to those who engage in multiple athletic activities.
Price Comparison
The Brooks Glycerin GTS 22 is currently priced at $114.95, while the Nike Pegasus 41 is available for $111.67. This price difference of $3.28 translates to approximately 3% savings if you opt for the Nike model. While both prices are competitive within the running shoe market, the Pegasus 41 offers a slightly lower entry cost. However, the choice between these two shoes should not be made solely on price, as their features cater to different running styles and preferences.
Sales Rank and Popularity
In terms of popularity, the Brooks Glycerin GTS 22 has a sales rank of 2,097, indicating a strong position in the market. This rank suggests that it is a well-regarded option among runners seeking supportive footwear. Conversely, the Nike Pegasus 41 has a sales rank of 29,992, which is significantly lower. This disparity may reflect differing consumer preferences, with the Brooks model appealing more to those who prioritize support and stability.
Which should you buy?
Ultimately, the choice between the Brooks Glycerin GTS 22 and the Nike Pegasus 41 comes down to individual running needs and preferences. If you value superior support, stability, and versatility for various activities, the Brooks Glycerin GTS 22, priced at $114.95, is a solid choice. However, if you are looking for a lightweight shoe that excels in breathability and provides a responsive ride for road running, the Nike Pegasus 41 at $111.67 may be more appealing. Assess your specific requirements to find the best fit for your running adventures.

