Brooks Women’s Glycerin GTS 22 Supportive Running vs Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8
Updated August 2026 — Brooks Women’s Glycerin GTS 22 Supportive Running wins on support and comfort, Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 wins on weight.
The Brooks Glycerin GTS 22 excels in comfort and support, while the Saucony Endorphin Pro 4 focuses on speed and performance. Choose based on your running priorities.
Why Brooks Women’s Glycerin GTS 22 Supportive Running is better
Price
Brooks is $15.71 cheaper.
Support
Features GuideRails for stability.
Comfort
DNA Tuned cushioning provides plush landings.
Why Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 is better
Speed
Saucony is designed for race day performance.
Lightweight
Saucony is lighter for agility.
Performance
Carbon plate enhances responsiveness.
Overall score
Specifications
| Spec | Brooks Women’s Glycerin GTS 22 Supportive Running | Saucony Women's Endorphin Pro 4 Sneaker, Mirage/Citron, 8 |
|---|---|---|
| Cushioning | DNA Tuned | PWRRUN PB |
| Support System | GuideRails | None |
| Upper Material | Double Jacquard | Mesh |
| Weight | 10 oz | 8 oz |
| Best For | Comfort Runs | Racing |
Dimension comparison
Overview of the Brooks Glycerin GTS 22 and Saucony Endorphin Pro 4
The Brooks Glycerin GTS 22 is priced at $114.95, making it about 17% cheaper than the Saucony Endorphin Pro 4, which retails for $130.66. Both shoes are designed for running but cater to different preferences and needs. The Brooks model emphasizes support and cushioning, while the Saucony shoe focuses on speed and performance.
Design and Aesthetics
The Brooks Glycerin GTS 22 showcases a sleek design in a white, limpet shell, and amparo blue color scheme. Its modern aesthetic is complemented by a double jacquard knit upper that not only adds to its visual appeal but also enhances breathability and fit. On the other hand, the Saucony Endorphin Pro 4 comes in a striking mirage and citron colorway, emphasizing a sporty look. While both shoes are visually appealing, the Brooks model offers a more traditional running shoe appearance, whereas the Saucony’s design screams high-performance racing.
Comfort and Fit
Comfort is a significant factor in running shoes, and both models excel in this area but take different approaches. The Brooks Glycerin GTS 22 features DNA Tuned cushioning, which combines soft plush landings with responsive toe-offs, providing a luxurious feel during runs. Its accommodating fit ensures that runners experience comfort without sacrificing stability. In contrast, the Saucony Endorphin Pro 4 focuses on a lightweight, snappy feel, thanks to its PWRRUN PB cushioning and carbon plate. This design prioritizes speed but may not provide the same level of plush comfort as the Brooks shoe.
Support and Stability
When it comes to support, the Brooks Glycerin GTS 22 stands out with its innovative GuideRails support system designed to keep excess motion in check. This feature is particularly beneficial for those who require additional stabilization during their runs, making it a great choice for road runners and cross-trainers alike. Comparatively, the Saucony Endorphin Pro 4 emphasizes speed over support, utilizing a less supportive structure to maintain its lightweight profile, which may be less suitable for runners needing extra stability.
Performance on the Track
The performance capabilities of the Saucony Endorphin Pro 4 are geared towards speed and agility, making it a preferred choice for race day. Its lightweight construction and the combination of PWRRUN HG, PWRRUN PB, and a carbon plate contribute to a fast, responsive running experience. On the other hand, the Brooks Glycerin GTS 22 is designed for smooth transitions and steady pacing, making it ideal for longer runs where comfort is paramount. While both shoes can handle various running environments, the Saucony shoe excels in competitive settings, while the Brooks shoe focuses on comfort for everyday use.
Durability and Build Quality
Durability is crucial in running shoes, and both models are built to withstand regular use. The Brooks Glycerin GTS 22 features a robust upper that provides excellent breathability and durability. Its design is intended for runners who may frequent various terrains. The Saucony Endorphin Pro 4, while lightweight and fast, may not match the durability of the Brooks model due to its emphasis on a lightweight build. This distinction makes the Brooks shoe a potentially better long-term investment for those who run frequently.
Price Comparison
In terms of pricing, the Brooks Glycerin GTS 22 is priced at $114.95, which is $15.71 less than the Saucony Endorphin Pro 4 at $130.66. This price difference translates to about a 12% savings when opting for the Brooks model, making it not just a more economical choice but also one that offers high-quality features for runners seeking support and comfort.
Which should you buy?
Ultimately, your choice between the Brooks Glycerin GTS 22 and the Saucony Endorphin Pro 4 comes down to your specific running needs. If you prioritize comfort, support, and a more accommodating fit, the Brooks Glycerin GTS 22 is the clear winner, especially given its lower price point of $114.95. However, if speed and performance are your top priorities, and you are willing to invest a bit more at $130.66, the Saucony Endorphin Pro 4 will serve you well on race day. Each shoe has unique strengths that cater to different types of runners, so consider what aspects matter most to you before making your decision.

